Hedgehog pathway inhibitor
SMALL MOLECULES THAT INHIBIT THE ACTIVITY OF A COMPONENT OF THE HEDGEHOG SIGNALING PATHWAY
Hedgehog pathway inhibitors
Hedgehog pathway inhibitors, also sometimes called hedgehog inhibitors, are small molecules that inhibit the activity of a component of the Hedgehog signaling pathway. Due to the role of aberrant Hedgehog signaling in tumor progressionBerman DM, Karhadkar SS, Hallahan AR, Pritchard JI, Eberhart CG, Watkins DN, Chen JK, Cooper MK, Taipale J, Olson JM, Beachy PA.